Article
Different susceptibility to lung tumorigenesis in mice with an identical Kras2 intron 2.
Genomics - 20 Sept 1995
Manenti G, Falvella F S, Gariboldi M, Dragani T A, Pierotti M A
Abstract excerpt
The A/J mouse strain is genetically susceptible to pulmonary tumorigenesis. We have performed a genetic linkage analysis to map pulmonary adenoma susceptibility (Pas) loci in an urethane-treated (A/J x Mus spretus) x C57BL/6J (ASB) interspecific testcross. In this interspecific cross we have conf...
Topics
- Analysis of Variance
- Animals
- Base Sequence
- Chromosome Mapping
- Crosses, Genetic
- DNA Primers
- Deoxyribonucleases, Type II Site-Specific
- Exons
- Female
- Genetic Predisposition to Disease
- Introns
- Lung Neoplasms
- Male
- Mice
- Mice, Inbred A
- Mice, Inbred C57BL
- Molecular Sequence Data
- Muridae