Article
Different susceptibility to lung tumorigenesis in mice with an identical Kras2 intron 2.
Genomics - 20 Sept 1995
Manenti G, Falvella F S, Gariboldi M, Dragani T A, Pierotti M A
Abstract excerpt
The A/J mouse strain is genetically susceptible to pulmonary tumorigenesis. We have performed a genetic linkage analysis to map pulmonary adenoma susceptibility (Pas) loci in an urethane-treated (A/J x Mus spretus) x C57BL/6J (ASB) interspecific testcross. In this interspecific cross we have confirmed our previous results in AC3F2 mice on the mapping of the Pas1 locus to the distal region of chromosome 6, near...
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