Article
Ha-ras polymorphisms in epithelial ovarian cancer.
Gynecologic oncology - 1 Jun 1992
O'Briant K, Chrysson N, Hunter V, Tyson F, Tanner M, Daly L, George S L, Berchuck A, Soper J, Fowler W
Abstract excerpt
Unusual restriction fragment length polymorphisms (RFLPs) of the Ha-ras locus have been found in DNA from leukocytes and tumor tissue of cancer patients. To determine whether rare alleles would be observed frequently in patients with ovarian cancer, Ha-ras RFLPs were studied in DNA from 42 different ovarian epithelial tumors and from the peripheral blood leukocytes of 76 normal individuals. Four common, seven...
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