Article
Association of rare alleles of the Harvey ras protooncogene locus with lung cancer.
Cancer research - 15 Mar 1990
Sugimura H, Caporaso N E, Modali R V, Hoover R N, Resau J H, Trump B F, Longergan J A, Krontiris T G, Mann D L, Weston A
Abstract excerpt
The hypothesis that rare variable nucleotide tandem repeat alleles of the Ha-ras-1 polymorphism are an inherited predisposing factor in human lung carcinogenesis has been evaluated in an age, race, and smoking matched case-control study. Twenty-three different alleles were identified by their res...
Topics
- Adenocarcinoma
- Alleles
- Case-Control Studies
- Cells, Cultured
- DNA
- DNA, Neoplasm
- Gene Frequency
- Genes, ras
- Humans
- Lung Diseases, Obstructive
- Lung Neoplasms
- Lymphocytes
