Article
[Frequency and rearrangements of alleles of proto-oncogene c-Ha-ras-1 and their association with development of various malignant tumors in man].
Genetika - 1 Mar 1990
Nikiforova I F, Serova O M, Pluzhnikova G F, Kniazev P G, Seĭts I F
Abstract excerpt
The c-Ha-ras-1 locus in 84 cancer patients was examined for allelic restriction fragment length's polymorphism, as well as for distribution of four common c-Ha-ras-1 alleles (a1, a2, a3 and a4) in lung, ovarian and thyroid cancer patients. In approximately half (8 out of 15) lung and ovarian carc...
Topics
- Alleles
- Carcinoma
- Female
- Gene Frequency
- Gene Rearrangement
- Humans
- Lung Neoplasms
- Neoplasms
- Ovarian Neoplasms
- Polymorphism, Restriction Fragment Length
- Proto-Oncogene Mas
- Proto-Oncogenes
- Restriction Mapping
- Thyroid Neoplasms
