Allele diversity of the H-ras-1 variable number of tandem repeats in Norwegian lung cancer patients.

doi:10.1289/ehp.9298187

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Article

Allele diversity of the H-ras-1 variable number of tandem repeats in Norwegian lung cancer patients.

Environmental health perspectives - 1 Nov 1992

Ryberg D, Tefre T, Skaug V, Stangeland L, Ovrebø S, Naalsund A, Børresen A L, Haugen A

Abstract excerpt

We have examined restriction fragment length polymorphisms of the H-ras-1 gene in germ-line DNA from 214 lung cancer patients and 309 unaffected controls. When DNA samples were digested with MspI/HpaII, Southern blot analysis revealed at least 22 different alleles, grouped according to their freq...

Topics

Alleles
DNA, Neoplasm
Genes, ras
Humans
Lung Neoplasms
Norway
Polymorphism, Restriction Fragment Length
Repetitive Sequences, Nucleic Acid

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