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Article

X rays induce interallelic homologous recombination at the human thymidine kinase gene.

Molecular and cellular biology - 1 Jun 1992

Benjamin M B, Little J B

Abstract excerpt

We have developed a human lymphoblast cell line for the study of interchromosomal homologous recombination at the endogenous thymidine kinase (tk) gene on chromosome 17 (M. B. Benjamin, H. Potter, D. W. Yandell, and J. B. Little, Proc. Natl. Acad. Sci. USA 88:6652-6656, 1991). This cell line (designated 6:86) carries unique heterozygous frameshift mutations in exons 4 and 7 of its endogenous tk alleles and can...

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Identifiers

PMID: 1350323
DOI: 10.1128/mcb.12.6.2730-2738.1992
PMCID: PMC364467

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