Article
Genetic classification of combined hepatocellular-cholangiocarcinoma.
Human pathology - 1 Sept 2000
Fujii H, Zhu X G, Matsumoto T, Inagaki M, Tokusashi Y, Miyokawa N, Fukusato T, Uekusa T, Takagaki T, Kadowaki N, Shirai T
Abstract excerpt
Combined hepatocellular-cholangiocarcinoma (combined HCC/ CC) is a rare form of liver neoplasms showing both hepatocellular (HCC) and bile duct differentiation (CC). In an attempt to clarify the clonality and genetic/phenotypic relationships in the evolution of these neoplasms, we microdissected multiple HCC and CC foci and studied allelic status of chromosome arms 1p, 1q, 3p, 4q, 5q, 6q, 8p, 9p, 10q, 11q, 13q,...
Topics
- Aged
- Alleles
- Bile Duct Neoplasms
- Carcinoma, Hepatocellular
- Cell Separation
- Cholangiocarcinoma
- Chromosomes, Human
- Clone Cells
- DNA, Neoplasm
- Female
- Humans