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Genotype stability and clonal evolution of hepatocellular carcinoma assessed by autopsy-based genome-wide microsatellite analysis.

Cancer genetics and cytogenetics - 1 Sept 2005

Nishimura Takafumi, Nishida Naoshi, Komeda Toshiki, Fukuda Yoshihiro, Nakao Kazuwa

Abstract excerpt

It is widely accepted that chromosomal instability is an essential feature of cancer cells including hepatocellular carcinoma (HCC) cells. For an accurate characterization of clonal evolution of HCC cells, we studied chromosomal alterations in various metastatic lesions in an autopsy case of HCC. Tissues from the main tumor, which consisted of 2 macroscopically distinct portions, and from intrahepatic metastasis,...

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Identifiers

PMID: 16102588
DOI: 10.1016/j.cancergencyto.2005.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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