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Article

Virulence of non-type 1-fimbriated and nonfimbriated nonflagellated Salmonella typhimurium mutants in murine typhoid fever.

Infection and immunity - 1 Feb 1992

Lockman H A, Curtiss R

Abstract excerpt

The virulence of Salmonella typhimurium mutants that were unable to synthesize type 1 fimbriae was tested in a murine typhoid fever model. Nonfimbriated mutants (fim) exhibited a lower 50% lethal dose than a wild-type (fim+) strain and produced significantly higher mortality (fim, 55%; fim+, 37% [P less than 0.002]) in mice that were challenged orally. There was no difference in virulence when the wild-type and...

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Source

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Identifiers

PMID: 1346124
DOI: 10.1128/iai.60.2.491-496.1992
PMCID: PMC257654

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Source receipt: pubmed, retrieved 7 Sept 2026.

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