Article
A flagellated motile Salmonella Gallinarum mutant (SG Fla+) elicits a pro-inflammatory response from avian epithelial cells and macrophages and is less virulent to chickens.
Veterinary microbiology - 30 Aug 2013
de Freitas Neto Oliveiro Caetano, Setta Ahmed, Imre Ariel, Bukovinski Agnes, Elazomi Altaeb, Kaiser Pete, Berchieri Angelo, Barrow Paul, Jones Michael
Abstract excerpt
Salmonella enterica subspecies enterica serovar Gallinarum biovar Gallinarum (SG) is a non-flagellated bacterium which causes fowl typhoid, a systemic disease associated with high mortality in birds. It has been suggested that the absence of flagella in SG is advantageous in the early stages of systemic infection through absence of TLR-5 activation. In order to investigate this hypothesis in more detail a...
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