Article
The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin.
Journal of bacteriology - 1 May 1996
Schmitt C K, Darnell S C, O'Brien A D
Abstract excerpt
The flgM gene of Salmonella typhimurium encodes a negative regulator of flagellin synthesis that acts by inhibiting the flagellum-specific sigma factor FliA (sigma 28), but only when a mutation in a flagellar basal body, hook, or switch gene is present. We previously showed that FlgM is also necessary for the virulence of S. typhimurium in the mouse model of typhoid fever and proposed that FlgM is required to...
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