The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin.

doi:10.1128/jb.178.10.2911-2915.1996

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Article

The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin.

Journal of bacteriology - 1 May 1996

Schmitt C K, Darnell S C, O'Brien A D

Abstract excerpt

The flgM gene of Salmonella typhimurium encodes a negative regulator of flagellin synthesis that acts by inhibiting the flagellum-specific sigma factor FliA (sigma 28), but only when a mutation in a flagellar basal body, hook, or switch gene is present. We previously showed that FlgM is also nece...

Topics

Animals
Antigens, Bacterial
Bacterial Proteins
Flagellin
Lethal Dose 50
Mice
Mutation
Phenotype
Repressor Proteins
Salmonella typhimurium
Sigma Factor
Typhoid Fever
Virulence

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