Article
Multiple fimbrial adhesins are required for full virulence of Salmonella typhimurium in mice.
Infection and immunity - 1 Jun 1998
van der Velden A W, Bäumler A J, Tsolis R M, Heffron F
Abstract excerpt
Adhesion is an important initial step during bacterial colonization of the intestinal mucosa. However, mutations in the Salmonella typhimurium fimbrial operons lpf, pef, or fim only moderately alter mouse virulence. The respective adhesins may thus play only a minor role during infection or S. ty...
Topics
- Adhesins, Bacterial
- Animals
- Bacterial Adhesion
- Female
- Fimbriae, Bacterial
- Intestines
- Liver
- Mice
- Mice, Inbred BALB C
- Mutation
- Operon
- Salmonella typhimurium
- Spleen