Article
Construction and characterization of type 1 non-fimbriate and non-adhesive mutants of Salmonella typhimurium.
FEMS immunology and medical microbiology - 1 Dec 1997
Hancox L S, Yeh K S, Clegg S
Abstract excerpt
Mutations in the fimH gene of Salmonella typhimurium result in a non-fimbriate, non-adhesive phenotype. This phenotype was shown to be due to the lack of both fimH and fimF expression since disruption of the fimH gene by insertion of a DNA cassette into this determinant results in mutants that ar...
Topics
- Adhesins, Bacterial
- Adhesins, Escherichia coli
- Amino Acid Sequence
- Bacterial Adhesion
- Base Sequence
- Blotting, Southern
- Cell Line
- DNA, Bacterial
- Fimbriae Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- HeLa Cells
- Hemagglutination Tests
- Humans
- Molecular Sequence Data
- Multigene Family
- Mutagenesis, Insertional
- Phenotype