Loss of c-met protooncogene in primary and metastatic sites of breast cancer.

doi:10.1007/BF02303675

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Article

Loss of c-met protooncogene in primary and metastatic sites of breast cancer.

Annals of surgical oncology - 1 Sept 1997

Ng E H, Pey H B, Law H Y, Ng I, Ji C Y, Lin V, Soo K C

Abstract excerpt

BACKGROUND: It has been proposed that clones of tumor cells acquire higher metastatic potential as a result of specific genetic alterations. This study was designed to determine the role of the c-met protooncogene in systemic spread by comparing the loss of the c-met protooncogene between primary...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Blotting, Southern
Breast Neoplasms
Carcinoma
Combined Modality Therapy
DNA Probes
DNA, Neoplasm
Female
Humans
Lymphatic Metastasis
Middle Aged
Neoplasm Recurrence, Local
Polymerase Chain Reaction
Proto-Oncogene Proteins c-met
Retrospective Studies

Source

Open in PubMed

Identifiers

PMID: 9309340
DOI: 10.1007/BF02303675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9309340-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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