Article
Mutational analysis of the ST7 gene in human myeloid tumor cell lines.
Oncology reports - 1 Jan 2000
Sivasundaram Karnan, Suzuki Hiroko, Seto Masao, Hosokawa Yoshitaka
Abstract excerpt
The recently described ST7 (for suppression of tumorigenicity 7) gene has been suggested to be a major target gene on chromosome 7q31 for inactivation in a variety of human neoplasias. Loss of heterozygosity (LOH) in chromosome 7q31 is frequently observed in a variety of human neoplasias including malignant myeloid tumors. We, therefore, sought to examine a total of 22 human malignant myeloid tumor cell lines...
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