Article
Drosophila actin mutants and the study of myofibrillar assembly and function.
Symposia of the Society for Experimental Biology - 1 Jan 1992
Sparrow J C, Drummond D R, Hennessey E S, Clayton J D, Lindegaard F B
Abstract excerpt
The use of Drosophila mutations in the indirect flight muscle-specific actin gene, Act88F, to study actin structure/function and its assembly into thin filaments during myofibrillogenesis is described. Mutants with different phenotypic effects are discussed and attempts made to correlate the different properties of the mutants in vivo-myofibrillar structure, actin synthesis, accumulation and stability, heat shock...
Topics
- Actins
- Animals
- Drosophila
- Macromolecular Substances
- Microscopy, Electron
- Muscles
- Mutation
- Protein Processing, Post-Translational
- Structure-Activity Relationship
