Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterisation of missense mutations in the Act88F gene of Drosophila melanogaster.

Molecular & general genetics : MGG - 1 Apr 1991

Drummond D R, Hennessey E S, Sparrow J C

Abstract excerpt

We have created missense mutations in the indirect flight muscle (IFM)-specific Act88F actin gene of Drosophila melanogaster by random in vitro mutagenesis. Following P element-mediated transformation into wild-type flies and subsequent transfer of the inserts into Act88F null strains, the effects of the actin mutants on the structure and function of the IFMs were examined. All of the mutants were antimorphic for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cloning, Molecular
Share to DNA Transposable Elements
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscles

Share to Mutagenesis

Share to Mutation

Share to Phenotype

Share to Transformation, Genetic

Source

Identifiers

PMID: 1851957
DOI: 10.1007/BF00273589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterisation of missense mutations in the Act88F gene of Drosophila melanogaster.PMID 1851957Read ↗

Isolation of 88F actin mutants of Drosophila melanogaster and possible alterations in the mutant actin structures.Semantic proximity Read ↗

Heat shock gene activation by mutant actin is independent of myofibril degeneration in Drosophila muscle.Semantic proximity Read ↗

Expression and function of the Drosophila ACT88F actin isoform is not restricted to the indirect flight muscles.Semantic proximity Read ↗

Drosophila actin mutants and the study of myofibrillar assembly and function.Semantic proximity Read ↗

Differential epitope tagging of actin in transformed Drosophila produces distinct effects on myofibril assembly and function of the indirect flight muscle.Semantic proximity Read ↗

Drosophila indirect flight muscle specific Act88F actin mutants as a model system for studying congenital myopathies of the human ACTA1 skeletal muscle actin gene.Semantic proximity Read ↗

Functional and ultrastructural effects of a missense mutation in the indirect flight muscle-specific actin gene of Drosophila melanogaster.Semantic proximity Read ↗

Transcriptome analysis of IFM-specific actin and myosin nulls in Drosophila melanogaster unravels lesion-specific expression blueprints across muscle mutations.Semantic proximity Read ↗

Drosophila ACT88F indirect flight muscle-specific actin is not N-terminally acetylated: a mutation in N-terminal processing affects actin function.Semantic proximity Read ↗

Actin with tumor-related mutation is antimorphic in Drosophila muscle: two distinct modes of myofibrillar disruption by antimorphic actins.Semantic proximity Read ↗

Recovery of dominant, autosomal flightless mutants of Drosophila melanogaster and identification of a new gene required for normal muscle structure and function.Semantic proximity Read ↗

Insights into actomyosin interactions from actin mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.