Characterisation of missense mutations in the Act88F gene of Drosophila melanogaster.

doi:10.1007/BF00273589

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Article

Characterisation of missense mutations in the Act88F gene of Drosophila melanogaster.

Molecular & general genetics : MGG - 1 Apr 1991

Drummond D R, Hennessey E S, Sparrow J C

Abstract excerpt

We have created missense mutations in the indirect flight muscle (IFM)-specific Act88F actin gene of Drosophila melanogaster by random in vitro mutagenesis. Following P element-mediated transformation into wild-type flies and subsequent transfer of the inserts into Act88F null strains, the effect...

Topics

Actins
Animals
Cloning, Molecular
DNA Transposable Elements
Drosophila melanogaster
Electrophoresis, Gel, Two-Dimensional
Heat-Shock Proteins
Molecular Conformation
Muscles
Mutagenesis
Mutation
Myosins
Phenotype
Polymers
Transformation, Genetic

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