Article
SJL/J resistance to mouse hepatitis virus-JHM-induced neurologic disease can be partially overcome by viral variants of S and host immunosuppression.
Microbial pathogenesis - 1 Jul 1992
Pasick J M, Wilson G A, Morris V L, Dales S
Abstract excerpt
The basis of the resistance of SJL/J mice to various strains of mouse hepatitis virus (MHV) has been the subject of some debate, especially as it relates to the number and nature of the determinants involved. Our previous work demonstrated that resistance by primary SJL/J glial cultures may invol...
Topics
- Animals
- Base Sequence
- Cells, Cultured
- Central Nervous System Diseases
- Disease Susceptibility
- Genetic Variation
- Hepatitis, Viral, Animal
- Immunity, Innate
- Immunosuppression Therapy
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Murine hepatitis virus
- Neuroglia
- Sequence Deletion