Article
Infrequent mutation of p53 gene in hepatitis B virus positive primary hepatocellular carcinomas.
Oncogene - 1 Feb 1993
Hosono S, Chou M J, Lee C S, Shih C
Abstract excerpt
Somatic mutation of the p53 oncogene/anti-oncogene allele has been shown to be involved in many different human solid tumors. Recently, there have been reports that p53 mutations are found to occur at high frequency (50%) in aflatoxin-related human primary hepatocellular carcinomas (HCC) (Hsu et...
Topics
- Adult
- Aged
- Base Sequence
- Blotting, Southern
- Blotting, Western
- Carcinoma, Hepatocellular
- Chromosomes, Human, Pair 17
- Codon
- Exons
- Genes, p53
- Hepatitis B
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymorphism, Restriction Fragment Length