Article
p53 is not mutated in hepatocellular carcinomas from Alaska Natives.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
De Benedetti V M, Welsh J A, Trivers G E, Harpster A, Parkinson A J, Lanier A P, McMahon B J, Bennett W P
Abstract excerpt
Hepatocellular carcinoma is common among Alaska Natives. The known risk factor in this population is hepatitis B viral infection; fungal toxins, including aflatoxin B1, have not been detected in foodstuffs. In this series of 14 patients (including 4 siblings and 2 second cousins), 3 patients were less than 12 years old at diagnosis of hepatocellular carcinoma, 8 patients were 13-24 years old, and 3 patients were...
Topics
- Adolescent
- Adult
- Aged
- Alaska
- Antibodies
- Carcinoma, Hepatocellular
- Child
- Chromosome Deletion
- Chromosome Mapping
- Exons
- Female