Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations.

doi:10.1042/bj2870201

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Article

Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations.

The Biochemical journal - 1 Oct 1992

Dickens M, Chin J E, Roth R A, Ellis L, Denton R M, Tavaré J M

Abstract excerpt

The activation of insulin-stimulated protein-serine/threonine kinases has been investigated in CHO cell lines transfected with cDNAs encoding either wild-type or mutant human insulin receptors. (1) Insulin treatment of CHO cells over-expressing wild-type insulin receptors resulted in the rapid an...

Topics

Amino Acid Sequence
Animals
Blotting, Western
CHO Cells
Calcium-Calmodulin-Dependent Protein Kinases
Cricetinae
Cytosol
Enzyme Activation
Humans
Insulin
Molecular Sequence Data
Mutagenesis, Site-Directed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Protein Kinases

Protein Serine-Threonine Kinases

Protein-Tyrosine Kinases

Receptor, Insulin

Recombinant Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1329727
DOI: 10.1042/bj2870201
PMCID: PMC1133144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1329727-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations.PMID 1329727Read ↗

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