Article
Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells.
International journal of molecular sciences - 3 Apr 2015
Maeng Jeehye, Kim Miyoung, Lee Hyukjin, Lee Kyunglim
Abstract excerpt
Insulin induces the activation of Na,K-ATPase while translationally controlled tumor protein (TCTP) inhibits this enzyme and the associated pump activity. Because binding of insulin with its membrane receptor is known to mediate the phosphorylation of multiple intracellular proteins, phosphorylation of TCTP by insulin might be related to the sodium pump regulation. We therefore examined whether insulin induces...
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