Article
Head and neck cancer in nonsmokers: a distinct clinical and molecular entity.
The Laryngoscope - 1 Oct 1999
Koch W M, Lango M, Sewell D, Zahurak M, Sidransky D
Abstract excerpt
OBJECTIVES/HYPOTHESIS: Clinical and molecular patterns of head and neck squamous cell carcinoma (HNSCC) in nonsmokers and smokers may be different. Analysis of these patterns may improve understanding and management of this disease. STUDY DESIGN: three hundred five subjects were included (46 nonsmokers, 29 former smokers, and 230 smokers). Subsets were analyzed for p53 mutation, human papillomavirus (HPV), and...
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