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Article

Random diffusion can account for topA-dependent suppression of partition defects in low-copy-number plasmids.

Journal of bacteriology - 1 Aug 1992

Austin S J, Eichorn B G

Abstract excerpt

The maintenance of partition-defective (Par-) mini-P1 and mini-F plasmids was studied in topA strains of Escherichia coli, which are defective in topoisomerase I activity. The partition defects were substantially but not completely suppressed in broth-grown cultures. This suppression was not due to a large increase in copy number. However, the absolute number of copies of Par- mini-P1 plasmids per average...

Topics

DNA Topoisomerases, Type I
Diffusion
Escherichia coli
F Factor
Genes, Bacterial
Mutation
Plasmids

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1322881
DOI: 10.1128/jb.174.16.5190-5195.1992
PMCID: PMC206351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1322881-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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