Article
Silencing of genes flanking the P1 plasmid centromere.
Science (New York, N.Y.) - 22 Jan 1999
Rodionov O, Lobocka M, Yarmolinsky M
Abstract excerpt
Partition modules stabilize bacterial plasmids and chromosomes by actively promoting their segregation into daughter cells. The partition module of plasmid P1 is typical and consists of a centromere site, parS, and genes that encode proteins ParA and ParB. We show that ParB can silence genes flan...
Topics
- Bacterial Proteins
- Binding Sites
- Centromere
- Cross-Linking Reagents
- DNA Helicases
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Formaldehyde
- Gene Expression Regulation, Bacterial
- Genes, Reporter
- Mutation