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Article

Silencing of genes flanking the P1 plasmid centromere.

Science (New York, N.Y.) - 22 Jan 1999

Rodionov O, Lobocka M, Yarmolinsky M

Abstract excerpt

Partition modules stabilize bacterial plasmids and chromosomes by actively promoting their segregation into daughter cells. The partition module of plasmid P1 is typical and consists of a centromere site, parS, and genes that encode proteins ParA and ParB. We show that ParB can silence genes flanking parS (to which ParB binds), apparently by polymerizing along the DNA from a nucleation site at parS. Wild-type...

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Identifiers

PMID: 9915704
DOI: 10.1126/science.283.5401.546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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