Article
The P1 ParA protein and its ATPase activity play a direct role in the segregation of plasmid copies to daughter cells.
Molecular microbiology - 1 Sept 1996
Davis M A, Radnedge L, Martin K A, Hayes F, Youngren B, Austin S J
Abstract excerpt
The P1 ParA protein is an ATPase that recognizes the parA promoter region where it acts to autoregulate the P1 parA-parB operon. The ParB protein is essential for plasmid partition and recognizes the cis-acting partition site parS. The regulatory role of ParA is also essential because a controlle...
Topics
- Adenosine Triphosphatases
- Adenosine Triphosphate
- Bacterial Proteins
- Base Sequence
- Binding Sites
- DNA Footprinting
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Operator Regions, Genetic
- Operon
- Plasmids
- Promoter Regions, Genetic
- Protein Binding