Article
Altered ParA partition proteins of plasmid P1 act via the partition site to block plasmid propagation.
Molecular microbiology - 1 Sept 1997
Youngren B, Austin S
Abstract excerpt
The partition system of the P1 plasmid, P1par, consists of the ParA and ParB proteins and a cis-acting site, parS. It is responsible for the orderly segregation of plasmid copies to daughter cells. Plasmids with null mutations in parA or parB replicate normally, but missegregate. ParB binds specifically to the parS site, but the role of ParA and its ATPase activity in partition is unclear. We describe a novel...
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