Article
The role of Par proteins in the active segregation of the P1 plasmid.
Molecular microbiology - 1 Jul 2004
Li Yongfang, Dabrazhynetskaya Alena, Youngren Brenda, Austin Stuart
Abstract excerpt
The parS centromere-like site promotes active P1 plasmid segregation in the presence of P1 ParA and ParB proteins. At the modest growth rate used here, time-lapse and still photomicroscopy shows that the plasmid copies are clustered as a focus at the Escherichia coli cell centre. Just before cell division, the focus is actively divided and ejects bidirectionally into opposite halves of the dividing cell. In the...
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