Retinoic acid receptor expression during the in vitro differentiation of human neuroblastoma.

doi:10.1016/0304-3940(93)90572-3

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Article

Retinoic acid receptor expression during the in vitro differentiation of human neuroblastoma.

Neuroscience letters - 12 Nov 1993

Lovat P E, Pearson A D, Malcolm A, Redfern C P

Abstract excerpt

Neuroblastoma cells differentiate in response to retinoic acid and cyclic AMP. We have examined the expression of retinoic acid receptors (RARs) in relation to neuroblastoma differentiation and show that short term exposure of SK N SH, SH SY 5Y AND GI LI N cells to physiological concentrations of...

Topics

Blotting, Northern
Cell Differentiation
Humans
Neuroblastoma
Phenotype
Receptors, Retinoic Acid
Transcription, Genetic
Tumor Cells, Cultured

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