Article
Retinoic acid receptor expression during the in vitro differentiation of human neuroblastoma.
Neuroscience letters - 12 Nov 1993
Lovat P E, Pearson A D, Malcolm A, Redfern C P
Abstract excerpt
Neuroblastoma cells differentiate in response to retinoic acid and cyclic AMP. We have examined the expression of retinoic acid receptors (RARs) in relation to neuroblastoma differentiation and show that short term exposure of SK N SH, SH SY 5Y AND GI LI N cells to physiological concentrations of retinoic acid results in induction of RAR-beta, particularly the lower transcript. Cyclic AMP has no effect on...
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