Back to search

Article

Alterations of serine racemase expression determine proliferation and differentiation of neuroblastoma cells

2022-01-19

Abstract excerpt

Genetic deletion of serine racemase(SR) causes development disability of neuronal dendrites whereas increased expression of SR is found in differentiated cells in culture. These observations suggest roles of SR in cell proliferation and differentiation. Very recently,we have characterized increased SR expression when a neuroblastoma cell line,N2A,undergoes differentiation. However,whether and how the expression le...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1054d2b5-e1ed-54e6-90cd-74a25c1b268d
DOI
10.21203/rs.3.rs-1276348/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Alterations of serine racemase expression determine proliferation and differentiation of neuroblastoma cellsDOI 10.21203/rs.3.rs-1276348/v1
Essential role of GATA3 in regulation of differentiation and cell proliferation in SK-N-SH neuroblastoma cellsSemantic proximity
N6-methyladenosine–mediated overexpression of long noncoding RNA ADAMTS9-AS2 triggers neuroblastoma differentiation via regulating LIN28B/let-7/MYCN signalingSemantic proximity
Differential aminoacylase expression in neuroblastomaSemantic proximity
N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53.Semantic proximity
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastomaSemantic proximity
Sub-micromolar concentrations of retinoic acid induce morphological and functional neuronal phenotypes in SK-N-SH neuroblastoma cells.Semantic proximity
Sp4 controls constitutive expression of neuronal serine racemase and NF-E2-related factor-2 mediates its induction by valproic acid.Semantic proximity
MicroRNA Mediates DNA Demethylation Events Triggered by Retinoic Acid during Neuroblastoma Cell DifferentiationSemantic proximity
TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells.Semantic proximity
Methods used to achieve different levels of the neuronal differentiation process in SH‐SY5Y and Neuro2a cell lines: An integrative reviewSemantic proximity
CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo modelSemantic proximity
Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and CholesterolSemantic proximity
Select a neighboring publication to make it the new centre.