Article
Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.
American journal of human genetics - 1 Jul 1992
Tiret L, Rigat B, Visvikis S, Breda C, Corvol P, Cambien F, Soubrier F
Abstract excerpt
The hypothesis of a genetic control of plasma angiotensin I-converting enzyme (ACE) level has been suggested both by segregation analysis and by the identification of an insertion/deletion (I/D) polymorphism of the ACE gene, a polymorphism contributing much to the variability of ACE level. To elu...
Topics
- Adolescent
- Adult
- Analysis of Variance
- Base Sequence
- Child
- Female
- Genetic Linkage
- Genetic Variation
- Genotype
- Humans
- Linkage Disequilibrium
- Male