Article
Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study.
Circulation - 12 May 1998
O'Donnell C J, Lindpaintner K, Larson M G, Rao V S, Ordovas J M, Schaefer E J, Myers R H, Levy D
Abstract excerpt
BACKGROUND: There is controversy regarding the association of the angiotensin-converting enzyme deletion-insertion (ACE D/I) polymorphism with systemic hypertension and with blood pressure. We investigated these relations in a large population-based sample of men and women by using association an...
Topics
- Adult
- Aged
- Blood Pressure
- Cardiovascular Diseases
- Cohort Studies
- Female
- Genetic Linkage
- Genotype
- Human Growth Hormone
- Humans
- Hypertension
- Linear Models
- Male
- Microsatellite Repeats
- Middle Aged