Article
Polymorphism of the angiotensin I converting enzyme gene is apparently not related to high blood pressure: Dutch Hypertension and Offspring Study.
Journal of hypertension - 1 Apr 1993
Schmidt S, van Hooft I M, Grobbee D E, Ganten D, Ritz E
Abstract excerpt
OBJECTIVE: Studies in genetically hypertensive rats and their normotensive Wistar-Kyoto control rats have revealed a linkage of a chromosomal region containing the angiotensin converting enzyme (ACE) gene with blood pressure. This led to the hypothesis that ACE is a possible candidate gene for primary hypertension in humans. We defined the genotypes and allele frequencies of an insertion-deletion (I/D)...
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