Article
Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysis.
European journal of human genetics : EJHG - 1 Nov 2002
Brand Eva, Chatelain Nathalie, Paillard Françoise, Tiret Laurence, Visvikis Sophie, Lathrop Mark, Soubrier Florent, Demenais Florence
Abstract excerpt
Previous studies have suggested that angiotensinogen (AGT) gene variants are associated with increased plasma AGT levels, and may also contribute towards the inherited component of predisposition to essential hypertension in humans. To explore the potential functionality of several AGT polymorphisms and estimate their effects, together with other sources of familial correlations, on plasma AGT, we undertook a...
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