Plasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction.

doi:10.1161/01.cir.90.2.669

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Article

Plasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction.

Circulation - 1 Aug 1994

Cambien F, Costerousse O, Tiret L, Poirier O, Lecerf L, Gonzales M F, Evans A, Arveiler D, Cambou J P, Luc G

Abstract excerpt

BACKGROUND: The angiotensin-converting enzyme (ACE) plays an important role in the production of angiotensin II and the degradation of bradykinin, two peptides involved in cardiovascular homeostasy. Presence of a polymorphism in the ACE gene (ACE Ss) has been postulated from segregation analysis...

Topics

Alleles
Case-Control Studies
Genotype
Humans
Male
Middle Aged
Myocardial Infarction
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Regression Analysis
Risk Factors

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