Genetic factors in hypertension. Angiotensin-converting enzyme polymorphism.

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Article

Genetic factors in hypertension. Angiotensin-converting enzyme polymorphism.

Kardiologia polska - 1 Jul 2004

Czarnecka Danuta, Kawecka-Jaszcz Kalina, Stolarz Katarzyna, Olszanecka Agnieszka, Kieć-Wilk Beata, Dembińska-Kieć Aldona

Abstract excerpt

AIM: The key enzyme of the renin-angiotensin-aldosterone system angiotensin-converting enzyme (ACE), shows the genetic polymorphism responsible for the varying activity of this enzyme. In a study of randomly chosen families we analyzed the relationship between insertion/deletion (I/D) polymorphism of the ACE and ambulatory blood pressure (ABP), left ventricular mass index (LVMI) and carotid intima-media thickness...

Topics

Adult
Blood Pressure Monitoring, Ambulatory
Carotid Artery, Common
Female
Genotype
Humans
Hypertension
Hypertrophy, Left Ventricular
Male
Middle Aged
Peptidyl-Dipeptidase A
Polymerase Chain Reaction
Polymorphism, Genetic
Tunica Intima
Ultrasonography

Source

Open in PubMed

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PMID: 15338012

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