Article
Analysis of granulocyte-macrophage colony-stimulating factor action in differentiating myeloid leukemia cells: treatment with DMSO may reveal a common pathway for growth factor gene regulation.
Experimental hematology - 1 Mar 1991
Taetle R, Oval J, Smedsrud M, Davis C, Gansbacher B
Abstract excerpt
Previous studies showed that factor-independent, late-passage HL60 acute nonlymphocytic leukemia (ANLL) cells proliferated in response to granulocyte-macrophage colony-stimulating factor (GM-CSF) after treatment with dimethylsulfoxide (DMSO) or other agents inducing cellular differentiation. In the present studies, we examined mechanisms of this response. After treatment with DMSO, GM-CSF delayed expression of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.