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Article

Deregulated expression of the retinoid X receptor alpha prevents muscle differentiation in P19 embryonal carcinoma cells.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Sept 1998

Pratt M A, Crippen C, Hubbard K, Menard M

Abstract excerpt

We have studied the expression of the retinoid X receptor (RXR) family of receptors during the DMSO-induced differentiation of P19 murine embryonal carcinoma cells into mesoderm and muscle. RXR-alpha protein is weakly detectable in untreated P19 cells and in a mutant line of P19 cells (D3) that a...

Topics

Administration, Topical
Animals
Anti-Inflammatory Agents
Carcinoma, Embryonal
Cell Death
Cell Differentiation
Clone Cells
Dimethyl Sulfoxide
Gene Expression Regulation, Neoplastic
Muscles
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Receptors, Retinoic Acid

Retinoid X Receptors

Transcription Factors

Tumor Cells, Cultured

Source

Identifiers

PMID: 9751115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9751115-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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