Article
Induction of growth suppression and modification of gene expression in multi-drug-resistant human glioblastoma multiforme cells by recombinant human fibroblast and immune interferon.
International journal of cancer - 28 May 1992
Moulton T A, Jiang H, Guarini L, Fetell M R, Fisher P B
Abstract excerpt
The combination of recombinant human fibroblast (IFN-beta) and immune (IFN-gamma) interferon induces enhanced growth suppression and modifies the antigenic phenotype in parental and multi-drug-resistant (MDR) human glioblastoma multiforme (GBM) cells. The present study was conducted to explore th...
Topics
- Cell Division
- Colchicine
- Dose-Response Relationship, Drug
- Drug Combinations
- Drug Resistance
- Gene Expression Regulation, Neoplastic
- Glioblastoma
- Humans
- Interferon-beta
- Interferon-gamma
- Phenotype