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Article

Interferon inhibition of neoplastic phenotype in cell lines harbouring human papillomavirus sequences.

Journal of biological regulators and homeostatic agents - 1 Jan 2000

De Marco F, Di Lonardo A, Venuti A, Marcante M L

Abstract excerpt

The transformed phenotype is markedly affected by Interferon (IFN) long term treatment in HeLa and Siha cell lines. Two months of continuous exposure to 100 and 1000 International Units (IU)/ml of human recombinant alpha IFN causes a drastic reduction of anchorage independent growth in soft-agar. No effect on in vitro growing potential was observed at the same concentrations. This antiproliferative effect in...

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PMID: 1716817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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