Oncogene expression is modulated by recombinant human interferon-beta in human breast-cancer cells.

doi:10.1002/(SICI)1097-0215(19960729)67:3<441::AID-IJC21>3.0.CO;2-9

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Article

Oncogene expression is modulated by recombinant human interferon-beta in human breast-cancer cells.

International journal of cancer - 29 Jul 1996

Sica G, Angelucci C, Marini L, Milazzo F, Donini S

Abstract excerpt

The effect of recombinant human interferon-beta on growth and oncoprotein expression was investigated in several human breast-cancer cell lines with different characteristics. All cell lines tested were sensitive to the antiproliferative action of the drug, regardless of their estrogen sensitivit...

Topics

Antineoplastic Agents
Breast Neoplasms
Cell Division
Gene Expression
Humans
Interferon alpha-2
Interferon-alpha
Interferon-beta
Oncogene Proteins
Phenotype
Proto-Oncogene Proteins c-myc
Proto-Oncogene Proteins p21(ras)
RNA, Messenger
Receptor, ErbB-2
Recombinant Proteins
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8707422
DOI: 10.1002/(SICI)1097-0215(19960729)67:3<441::AID-IJC21>3.0.CO;2-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8707422-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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