Article
Oncogene expression is modulated by recombinant human interferon-beta in human breast-cancer cells.
International journal of cancer - 29 Jul 1996
Sica G, Angelucci C, Marini L, Milazzo F, Donini S
Abstract excerpt
The effect of recombinant human interferon-beta on growth and oncoprotein expression was investigated in several human breast-cancer cell lines with different characteristics. All cell lines tested were sensitive to the antiproliferative action of the drug, regardless of their estrogen sensitivity. The maximal inhibition of cell proliferation was seen after 6 days of treatment. In estrogen-sensitive CG-5 and...
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