Article
Effect of radiation on cytokine and cytokine receptor messenger-RNA profiles in p53 wild and mutated human glioblastoma cell lines.
Clinical and investigative medicine. Medecine clinique et experimentale - 1 Apr 2001
Yee D, Hao C, Cheung H C, Chen H T, Dabbagh L, Hanson J, Coupland R, Petruk K C, Fulton D, Roa W H
Abstract excerpt
OBJECTIVE: Glioblastoma cells produce cytokines with proinflammatory or immunosuppressive properties, or both, which, in addition to altered p53 gene expression, have been shown to be associated with glioblastoma resistance to radiotherapy. The reported data concerning cytokines have been isolated and sometimes discordant, and a comprehensive profile analysis of cytokines and their corresponding receptors in...
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