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Article

Effect of IFN-β on human glioma cell lines with temozolomide resistance

4 Jun 2009

Abstract excerpt

Human interferon-beta (IFN-beta) is known to exhibit pleiotropic biological activities including antitumor effects. On the other hand, temozolomide (TMZ), an oral bioavailable alkylating agent with excellent tolerability, has demonstrated efficacy and has become a key therapeutic agent in patients with malignant gliomas; however, its survival benefit remains unsatisfactory. More recent studies have indicated that...

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PMID: 19513561
DOI: 10.3892/ijo_00000322

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