Article
The sequence context of the initiation codon in the encephalomyocarditis virus leader modulates efficiency of internal translation initiation
1 Apr 1992
Abstract excerpt
Translation initiation on poliovirus and encephalomyocarditis virus (EMCV) mRNAs occurs by a cap-independent mechanism utilizing an internal ribosomal entry site (IRES). However, no unifying mechanism for AUG initiation site selection has been proposed. Analysis of initiation of mRNAs translated in vitro has suggested that initiation of poliovirus mRNA translation likely involves both internal binding of...
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