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Article

Crystal structure of human GDF11

15 Feb 2016

Abstract excerpt

Members of the TGF-β family of proteins are believed to play critical roles in cellular signaling processes such as those involved in muscle differentiation. The extent to which individual family members have been characterized and linked to biological function varies greatly. The role of myostatin, also known as growth differentiation factor 8 (GDF8), as an inhibitor of muscle differentiation is well understood...

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PMID: 26919518
DOI: 10.1107/s2053230x16001588

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