Article
Involvement of Fis protein in replication of the Escherichia coli chromosome.
Journal of bacteriology - 1 Jan 1992
Filutowicz M, Ross W, Wild J, Gourse R L
Abstract excerpt
We report evidence indicating that Fis protein plays a role in initiation of replication at oriC in vivo. At high temperatures, fis null mutants form filamentous cells, show aberrant nucleoid segregation, and are unable to form single colonies. DNA synthesis is inhibited in these fis mutant strains following upshift to 44 degrees C. The pattern of DNA synthesis inhibition upon temperature upshift and the...
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