Article
Ki-ras codon 12 point mutation and p53 mutation in pancreatic diseases.
Hepato-gastroenterology - 1 Jan 2000
Yamaguchi K, Chijiiwa K, Noshiro H, Torata N, Kinoshita M, Tanaka M
Abstract excerpt
BACKGROUND/AIMS: The Ki-ras gene located at 12p, encodes the GTP binding protein involving the signal transduction system and concerns cell proliferation and differentiation. METHODOLOGY: Pancreatic tissues were obtained from 37 patients with various pancreatic diseases. Ki-ras codon 12 point mutation and p53 (exon 5-8) mutation were examined in 3 patients with chronic pancreatitis, 9 mucinous adenoma of the...
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