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Article

Prevalence of Activating K-ras Mutations in the Evolutionary Stages of Neoplasia in Intraductal Papillary Mucinous Tumors of the Pancreas

1 Oct 1997

Abstract excerpt

OBJECTIVE: The purpose of the study was to determine the prevalence of activating K-ras mutations in the pancreas of patients with intraductal papillary mucinous tumors (IPMT) and to analyze their relation to the degree of site-specific histopathologic abnormality. BACKGROUND: Intraductal papillary mucinous tumors of the pancreas have a biologic behavior that is significantly different from pancreatic ductal...

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Identifiers

PMID: 9351717
DOI: 10.1097/00000658-199710000-00010

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