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Article

Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes.

Journal of virology - 1 Jan 1992

Rowe M, Lear A L, Croom-Carter D, Davies A H, Rickinson A B

Abstract excerpt

Previous studies on Epstein-Barr virus (EBV)-positive B-cell lines have identified two distinct forms of virus latency. Lymphoblastoid cell lines generated by virus-induced transformation of normal B cells in vitro, express the full spectrum of six EBNAs and three latent membrane proteins (LMP1, LMP2A, and LMP2B); furthermore, these lines often contain a small fraction of cells spontaneously entering the lytic...

Topics

Antigens, Viral
B-Lymphocytes
Base Sequence
Blotting, Western
DNA, Viral
Epstein-Barr Virus Nuclear Antigens
Fluorescent Antibody Technique
Gene Expression Regulation, Viral
Herpesvirus 4, Human
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Tetradecanoylphorbol Acetate

Transcriptional Activation

Viral Matrix Proteins

Virus Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 1309242
DOI: 10.1128/JVI.66.1.122-131.1992
PMCID: PMC238267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1309242-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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