Article
Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes.
Journal of virology - 1 Jan 1992
Rowe M, Lear A L, Croom-Carter D, Davies A H, Rickinson A B
Abstract excerpt
Previous studies on Epstein-Barr virus (EBV)-positive B-cell lines have identified two distinct forms of virus latency. Lymphoblastoid cell lines generated by virus-induced transformation of normal B cells in vitro, express the full spectrum of six EBNAs and three latent membrane proteins (LMP1, LMP2A, and LMP2B); furthermore, these lines often contain a small fraction of cells spontaneously entering the lytic...
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