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Epstein–Barr Virus B Cell Growth Transformation: The Nuclear Events

24 Mar 2023

Abstract excerpt

Epstein-Barr virus (EBV) is the first human DNA tumor virus identified from African Burkitt's lymphoma cells. EBV causes ~200,000 various cancers world-wide each year. EBV-associated cancers express latent EBV proteins, EBV nuclear antigens (EBNAs), and latent membrane proteins (LMPs). EBNA1 tethers EBV episomes to the chromosome during mitosis to ensure episomes are divided evenly between daughter cells. EBNA2...

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PMID: 37112815
DOI: 10.3390/v15040832

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